Eye / Vision

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Multifunctional small molecule TLR4 antagonist for treating ocular neovascularization

Suchismita Acharya PhD, UNT Health Science Center
Santosh K. Panda PhD, AyuVis Reseach
Jiyang Cai PhD, University of Texas Medical Branch
Dorota L. Stankowska PhD, UNT Health Science Center
Rafael Ufret-Vincenty MD, UT Southwestern Medical Center

RAD Assignment Number: 1000

Presentation Type: poster

C1q induction and glial activation following optic nerve injury

Elliott Allums, UNT Health Science Center
Yang Liu, North Texas Eye Research Institute, UNT Health Science Center
Abbot F. Clark, North Texas Eye Research Institute, UNT Health Science Center

RAD Assignment Number: 1001

Presentation Type: poster

Endothelin Mediated Changes in Gene Expression Determined by RNA-sequencing of the Translatome in Primary Retinal Ganglion Cells.

Renuka M. Chaphalkar, UNT Health Science Center
Raghu R. Krishnamoorthy, UNT Health Science Center
Dorota L. Stankowska PhD, UNT Health Science Center

RAD Assignment Number: 1002

Presentation Type: poster

Application of the CRISPR interference method in regulating TGFβ2 in the trabecular meshwork

Daniel Goan, UNT Health Science Center
Nghia Nguyen, UNT Health Science Center
Hannah Webber, UNT Health Science Center
Jaclyn Bermudez, UNT Health Science Center
Abbot F. Clark, UNT Health Science Center
Weiming Mao, UNT Health Science Center

RAD Assignment Number: 1003

Presentation Type: poster

Neuroprotective effects of an endothelin receptor antagonist in a rat model of ocular hypertension.

Hayden B. Jefferies B.S., UNT Health Science Center
Nolan McGrady B.S., UNT Health Science Center
Raghu Krishnamoorthy PhD, UNT Health Science Center

RAD Assignment Number: 1004

Presentation Type: poster

Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma

Ramesh Babu Kasetti, UNT Health Science Center
Prabhavathi Maddineni, UNT Health Science Center
Pinkal Patel, UNT Health Science Center
Cameron Millar PhD, UNT Health Science Center
Tien Phan, UNT Health Science Center
Charles Searby, University of Iowa
Abbot F. Clark, UNT Health Science Center
Val Sheffield, University of Iowa
Gulab Zode, UNT Health Science Center

RAD Assignment Number: 1005

Presentation Type: poster

Role of Glutaredoxin 2 (Grx2) in protecting the retina from light-induced damage

Xiaobin Liu, UNT Heatlh Science Center
Christy Xavier, UNT Health Science Center
Hongli Wu, School of Pharmacy

RAD Assignment Number: 1006

Presentation Type: poster

Transforming Growth Factor β2 Regulates the Expression of microRNAs (miRNAs) in Human Optic Nerve Head Cells

Navita N. Lopez MSc, UNT Health Science Center
Tara Tovar-Vidales PhD, UNT Health Science Center
Abbot F. Clark PhD, UNT Health Science Center

RAD Assignment Number: 1007

Presentation Type: poster

Overexpression of ATF-4 in trabecular meshwork causes elevation of intra ocular pressure and reduction of outflow facility in a CHOP dependent manner

Prabhavathi Maddineni, UNT Health Science Center
Ramesh Kasetti, UNT Health Science Center
Gulab Zode, UNT Health Science Center

RAD Assignment Number: 1008

Presentation Type: poster

Endothelin receptors are targets for neuroprotection in a rat model of glaucoma

Nolan R. McGrady, UNT Health Science Center
Dorotoa L. Stankowska, UNT Health Science Center
Caitlin Rendon, Texas Lutheran University
Raghu R. Krishnamoorthy, UNT Health Science Center

RAD Assignment Number: 1009

Presentation Type: poster

Protective effect of ID protein on TGFβ2 induced fibrosis in human trabecular meshwork cells: implication for developing a glaucoma therapy.

Avani A. Mody, UNT Health Science Center
J. Cameron Millar, UNT Health Science Center
Robert J. Wordinger PhD, UNT Health Science Center
Abbot F. Clark, UNT Health Science Center

RAD Assignment Number: 1010

Presentation Type: poster

Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension and glaucoma in mice

Gaurang C. Patel, North Texas Eye Research Institute, UNT Health Science Center
Yang Liu, North Texas Eye Research Institute, UNT Health Science Center
J. Cameron Millar, North Texas Eye Research Institute, UNT Health Science Center
Abbot F. Clark, North Texas Eye Research Institute, UNT Health Science Center

RAD Assignment Number: 1011

Presentation Type: poster

A Small Chemical Chaperone, Sodium 4 Phenylbutyrate Inhibits TGFβ2-Induced ECM Remodeling in Human TM Cells

Pinkal D. Patel, UNT Health Science Center
Ramesh Babu Kasetti, UNT Health Science Center
Tien Phan, UNT Health Science Center
Prabhavathi Maddineni, UNT Health Science Center
Gulab Zode, UNT Health Science Center

RAD Assignment Number: 1012

Presentation Type: poster

Tissue Transglutaminase Mediated Ocular Hypertension and Effects of a Small Molecule Crosslinking Modulator

Urmimala Raychaudhuri, UNT Health Science Center
Cameron Millar PhD, UNT Health Science Center
Abbot F. Clark, UNT Health Science Center

RAD Assignment Number: 1013

Presentation Type: poster

Crosstalk Between TGFβ2 and TLR-4 Signaling Pathways in the Glaucomatous Trabecular Meshwork

Amanda Lenell Roberts, UNT Health Science Center
Humberto Hernandez, UNT Health Science Center
Stacy Curry, UNT Health Science Center
Colleen McDowell, UNT Health Science Center

RAD Assignment Number: 1014

Presentation Type: poster

An Antiapoptotic Peptide for Neuroprotection in Glaucoma

Dorota L. Stankowska PhD, UNT Health Science Center
Raghu R. Krishnamoorthy, UNT Health Science Center
Sruthi Sampathkumar, Case Western Reserve University
Ram Nagaraj, University of Colorado School of Medicine

RAD Assignment Number: 1015

Presentation Type: poster

Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork

Humberto Hernandez, UNT Health Science Center
Wanda E. Medina-Ortiz, UNT Health Science Center
Stacy Curry, UNT Health Science Center
Tomi Luan, UNT Health Science Center
Abbot F. Clark, UNT Health Science Center
Colleen M. McDowell, UNT Health Science Center

RAD Assignment Number: 1016

Presentation Type: oral

Effects of Wnt/beta-catenin and SMAD/TGF-beta crosstalk on cadherins in the trabecular meshwork

Hannah C. Webber, UNT Health Science Center
Weiming Mao, UNT Health Science Center
Abbot F. Clark, UNT Health Science Center

RAD Assignment Number: 1017

Presentation Type: poster