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Theses/Dissertations from 2017

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Adaptation of the Genetic Risk Prediction Model BRCAPRO for Primary Care Settings, Philamer M. Atienza

“Ecstasy” to Addiction: Mechanistic and Reinforcing Effects of Synthetic Cathinone Analogs of MDMA, Sean B. Dolan

Mechanisms of Sympathoexcitation via Hyper-Acute Intermittent Hypoxia in Humans: Implications for Obstructive Sleep Apnea, Noah P. Jouett

Creating novel purification and biochemical characterization protocols for C. collagenase from Clostridium histolyticum, developing a new emergency medicine product, and formulating several novel therapies for chronic and acute wound treatment, Jason P. Mars

Measurement of Traumatic Brain Injury (TBI) Inpatient Activity Levels Through Accelerometry, Jeffrey T. Ramsey

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Assisting the Implementation of a Centralized IRB in Multiple Categories of Research at Medical City of Fort Worth, Pawanpreet Randhawa

Approaches to mitochondrial genome sequencing using the oxford nanopore minion device, Kelcie C. Thorson

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Obstacles Associated with Physician Referral of Patients into Clinical Trials, Nick Torrez

Theses/Dissertations from 2016

Comparative assessment of IV acetaminophen and conscious sedation for pain relief during invasive cardiac procedures, Zainab I. Alam

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Sponsor Accrual of Investigative Add-On Sites, Eli Arbov

Benefits, Challenges, and Future Directions: Making the Case for eTMF in Clinical Research, Amber C. Beckham

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Barriers to Completion of a Family Health History Tool and Increasing Subject Retention, Margarett A. Bennett

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Exploring Trabecular Meshwork Molecular Pathogenic Mechanisms In Primary Open Angle Glaucoma And Glucocorticoid Induced Glaucoma, Jaclyn Y. Bermudez

Development and Characterization of Methylene Blue Oleate Salt-Loaded Polymeric Nanoparticles as a Treatment for Glioblastoma, Jessica M. Castañeda-Gill

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Variation in the Branching Pattern of the Internal Iliac Artery, Jeff Chase

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Submission to the IRB: Will Modified Training Improve the Probability of Successful Submission of IRB Protocols?, Yuhung H. Chou

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Implementation of an Updated Standard Operating Procedure For Investigational Product Management, Johnny V. Dang

Study of Kinematics and Gait in Dynamic Response Feet across Functional K-Level Categories., Russell J. Donevant

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Effect of Phosphorylation on Muscle Physiology and Biophysical Characterization of Mutations Responsible for Familial Hypertrophic Cardiomyopathy, Divya Duggal

Statins and PCSK9 Inhibitors: How They Have Shaped Medicine, A Comparative Review, Phillip R. Escarsega

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Astrocyte-mediated HIV-1 Tat neurotoxicity and its molecular mechanisms: astrocyte activation and impaired neurogenesis, Yan Fan

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Multiple primary cancers in survivors of adolescent and young adult cancers in the United States, SEER 1973-2012, Lauren R. Hall

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SR-B1 directed nanoparticles as a drug delivery system for the treatment of triple negative breast cancer, Rebecca A. Johnson

The Role of Cerebral Oxygenation and Perfusion on Tolerance to Central Hypovolemia, Victoria L. Kay

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Inorganic nanoparticles for applications in biomedical sciences, Bhuvaneswari Koneru

Comparison of Deparaffinization Methods with DNA Quantification, Raechal P. Leonard

MaCHTools: Additional functionality for the imputation software MaCH, Jeffrey S. Mitchel Jr.

The Role of Free Radicals in the Exercise Induced Resetting of the Arterial Baroreflex, Gilbert Moralez

Human Blood versus Two Commercially Available Blood Substitutes: A Comparative Analysis, Katharine M. Murphy

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A Cadaveric Investigation of the Dorsal Scapular Nerve, Vuvi H. Nguyen

The role of exosomes and microRNA in Astrocyte-mediated HIV-1 Tat neurotoxicity, Pejman Rahimian

Quantitative Proteomic Investigation of Estrogenic Endocrine-Disrupting Effects in the Rat Uterus, Fatima R. Rahlouni

Multiplex of INDELs for Human Identification Markers, Kelly A. Sage

The Role of Angiotensin II in Central Control of Blood Pressure and Body Fluid Homeostasis, Brent Shell

Epigenetic Regulation of Gene Expression in Alzheimer’s disease, Shantanu J. Shewale

A Novel Multiplex Assay for an Ancestry-Informative Marker (AIM) Panel of INDELs, Sarah A. Sturm

Identifying Risk Factors for 30-Day Readmissions in Patients with Cirrhosis, Stephen L. Tan

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Views on Clinical Trials, Bryan Q. Tran

Extracellular Superoxide Dismutase Indirectly Enhances the Release of Immature Neutrophils from the Murine Bone Marrow, Alexandra R. Witter

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Admixture Effects on Coevolved Metabolic Systems, Roxanne R. Zascavage

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Selection of Highly Informative Markers for Apportionment of Ancestry and Population Affiliation, Xiangpei Zeng

Theses/Dissertations from 2015

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Developmental and Internal Validation of a Mitochondrial DNA Direct Amplification Kit for Forensic Reference Samples, Alessandra Alicea-Centeno B.S.

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Analysis of Efficiency and User Satisfaction Following the Introduction of Digital Source Documents and Resources in a Clinical Research Setting, Marlena C. Alosi

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Comparison of Next Generation Sequencing Methodology on the Ion PGM™ System Performance versus that on the Sanger Sequencing Method for HV1 and HV2 Regions of mtDNA, Wendy C. Argueta B.S.

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Risk of Hematopoietic Cancer Associated Mortality among Workers in the Poultry Slaughtering and Processing Industries, Saritha Bangara M.P.H

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Healthcare Provider Barriers to Family Health History Clinical Decision Support Tools, Victoria R. Baria

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Effect of Collagenase Type 2 and Proteinase K Digestion on DNA Yield from Bone Samples Purified on the EZ1 Advanced XL, Lisa C. Barrett

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Comparative study of the physical symptoms following bilateral mastectomy with immediate breast reconstruction and delayed breast reconstruction, Ritika U. Bhat M.B.B.S.

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Evaluation of NK Cell – Astrocyte Interactions: Potential Role in HIV-Associated Neurocognitive Disorders and HIV- Associated Dementia, Kelly E. Bowen B.A.

Aging of the Thymic Epithelial Progenitor Pool is Determined by the p63-FoxN1 Regulatory Axis, Preston I. Burnley

Converting from Paper-Based to Electronic Data Capture and Record Keeping in Clinical Trial Management: Benefits, Challenges and Practical Considerations, Colton Castle

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Trace amine associated receptor 1 (TAAR1), a novel astrocyte receptor for METH-mediated neurotoxicity in HIV-1-associated neurocognitive disorders (HAND), Irma E. Cisneros

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Thymic involution perturbs negative selection and leads to chronic inflammation, Brandon D. Coder B.S.

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Characterization and Optimization of Nanoparticles for Polynucleotide delivery, Bhavani Saranya Conjeevaram Nagarajan

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Ancestry Informativeness of Alu Markers in Four Populations Relevant for the United States, Aislinn G. D'Auben

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Intermittent hypoxia induced opioidergic protection of the heart, Juan A. Estrada

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Discovery and Characterization of Tetranucleotide Short Tandem Repeats in North American Bears (Ursids), Michelle L. Graham B.S.

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Genetic Diversity in Sioux Indians of South Dakota with 21 Autosomal STR Loci and Their Forensic Utility, Nicole C. Grubb

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Genetic Diversity of Easter Island (Rapanui) Population from Identifiler® Plus autosomal, Y-filer®, and Y-Plex™ 6 Y-STR Loci, Laura Guadian B.S.

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Advanced Problem Solving in the Biotherapeutics Industry: Parameters influencing the delivery of a novel cell therapy product and exploration of a new method for determining activity of Clostridium histolyticum collagenase, a wound debridement enzyme, Melanie A. Harris B.S.

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Effect of creatine on nociception in a mouse model of inflammatory pain, Haydee S. Izurieta Munoz

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Validation of Droplet Digital PCR (ddPCR) for the Detection and Absolute Quantification of Borrelia DNA in Ixodes Ticks, Jenny L. King

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Formulation, characterization and validation of CpG functionalized PLGA bacteriomimetic nanoparticles for breast cancer immunotherapy, Rutika A. Kokate

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The Effects of Known PCR Inhibitors on Droplet Digital PCR Performance, William Patrick Kolar

MIEN1 Drives Breast Cancer Invasion by Regulating Cytoskeletal-Focal Adhesions Dynamics, Marilyne F. Kpetemey B.S.

Investigation of Anterior Cruciate Ligament Fibroblast Biomarkers for Cell Characterization by Immunohistochemistry, Tanya Lerma

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Intercellular Nef transfer and HIV-1 infection of astrocytes, Xiaoyu Luo

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Role of Exosomal Annexin A2 in Angiogenesis and Breast Cancer Metastasis, Sayantan Maji

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Evaluating Noise and the Implications of Methodology in the Analytical Threshold Designation for Forensic Genetic Analysis, Ashley N. Malone B.S.

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The Association between Health Literacy and Diabetes Outcomes and Self-Management Behaviors among Older Adults in the U.S, Maria F. Montoya

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Discovering the Optimal Hair Sections for Mitochondrial DNA Quantification via a Multiplex Real-Time PCR Assay, Meriam I. Nakhla

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Analysis of Patient Practices and Attitudes towards Compliance with Contact Lens Storage Cases in Relation to Microbial Contamination Levels, Sarah B. Ndedi

Possible Fluoride Toxicity in North America: a paleopathological assessment and discussion of modern occurrence, Elizabeth A. Nelson

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The Analysis of Current Recruitment Methods: Measuring the Potential of Social Media in Clinical Research Trials, Denise T. Nguyen

Polymorphism of Y-STR haplotypes is governed by patrilineal ancestry combined with effects of male migration, Michael R. Nolan

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Cell line authentication and contamination assessment for human cell cultures, Andrea Ormos B.S.

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The Flip-Flop of AMPA Receptors in Retinal Ganglion Cell Survival, Yong H. Park

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Neuroprotective Effects of Brn3b in PC12 Cells and Retinal Ganglion Cells under Glaucomatous Conditions, Nitasha R. Phatak

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Effects of Osteopathic Manipulative Treatment on the Inflammatory Mediators Related to Asthma, Christina E. Ragland

Dietary Curcumin And Caloric Restriction As Interventions For The Reversal Of Age Associated Functional Decline, Marjana R. Sarker

Antioxidants, Exercise, and Brain Function, Akram Sidhu

Pathological Mechanisms of Retinal Ischemia/Reperfusion Injury and Potential Targets of Neuroprotection, Sean M. Silverman

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Population Variances in the Whole Mitochondrial Genome Impacting Capture for Human Identification, Lisa A. Skandalis B.S.

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Increasing Knowledge of Patients in Clinical Trials Through New Means of Communication, Jordan E. Skrivanek

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Next-Generation Sequencing of Culture Negative Bronchoalveolar Lavage Reveals the Presence of Potentially Pathogenic Microorganisms, Ashley D. Smith B.S.

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Psalmotoxin-1 and nonproton ligand interactions with acid-sensing ion channels, Rachel N. Smith B.S.

Characterization of the interactions of guanidine compounds with the human GABA-A ρ1 receptor, Heather D. Snell

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The Effects of Chronic Intermittent Hypoxia on Oxidative Stress and Inflammation, Brina D. Snyder B.S.

Mitochondrial Genetics and Function among Men Screened for Prostate Cancer, Marc L. Sprouse

Mechanisms by which 17β-Estradiol (E2) suppress neuronal cox-2 expression, Winfred Stacey

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Selection of an Ancestry-Informative Marker (AIM) Panel of INDELs, Lindsey M. Thompson B.S.

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Assessment of Health Literacy and Potential Barriers Regarding Acceptance of the Human Papillomavirus (HPV) Vaccine Among Parents/Guardians, Brittany Vo-Le

Study of Kinematics in Individuals with Autism Spectrum Disorder and Developmental Coordination Disorder, Bylinda Vo-Le

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Development of a Comprehensive Massively Parallel Sequencing Panel of Single Nucleotide Polymorphism and Short Tandem Repeat Markers for Human Identification, David H. Warshauer

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Role of ΔFosB in nucleus of the solitary tract (NTS) in cardiovascular adaptations to chronic intermittent hypoxia (CIH) in rats, Qiong Wu M.B.B.S.

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Increasing Patient Recruitment Rates for Family Health History Support Tools, Julia Zhang

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Anatomical Variation of the Inferior Mesenteric Vein’s Drainage Pattern, Mina Zilaie B.S.

Theses/Dissertations from 2014

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Effects of Amicon Ultra-4 Centrifugal Devices on DNA Yield From Bone Samples and Effects of Amplicon Rx Post-PCR Treatment onRelative Florescence Units Obtained During Capillary Electrophoresis, Marie B. Amiel

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Role of catecholaminergic A2 neurons of nucleus of the solitary tract(NTS) in cardiovascular and respiratory adaptations to chronic intermittent hypoxia (CIH) in rats, Chandra Sekhar Bathina

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Osteopathic Management of Mild Leg Length Inequality with Heel Lift Therapy: A Pilot Study Analyzing Altered Gait Kinetics and Kinematics, Sebastiaan M. Bens