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Theses/Dissertations from 2015

Developmental and Internal Validation of a Mitochondrial DNA Direct Amplification Kit for Forensic Reference Samples, Alessandra Alicea-Centeno B.S.

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Analysis of Efficiency and User Satisfaction Following the Introduction of Digital Source Documents and Resources in a Clinical Research Setting, Marlena C. Alosi

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Comparison of Next Generation Sequencing Methodology on the Ion PGM™ System Performance versus that on the Sanger Sequencing Method for HV1 and HV2 Regions of mtDNA, Wendy C. Argueta B.S.

Risk of Hematopoietic Cancer Associated Mortality among Workers in the Poultry Slaughtering and Processing Industries, Saritha Bangara M.P.H

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Healthcare Provider Barriers to Family Health History Clinical Decision Support Tools, Victoria R. Baria

Effect of Collagenase Type 2 and Proteinase K Digestion on DNA Yield from Bone Samples Purified on the EZ1 Advanced XL, Lisa C. Barrett

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Comparative study of the physical symptoms following bilateral mastectomy with immediate breast reconstruction and delayed breast reconstruction, Ritika U. Bhat M.B.B.S.

Evaluation of NK Cell – Astrocyte Interactions: Potential Role in HIV-Associated Neurocognitive Disorders and HIV- Associated Dementia, Kelly E. Bowen B.A.

Aging of the Thymic Epithelial Progenitor Pool is Determined by the p63-FoxN1 Regulatory Axis, Preston I. Burnley

Converting from Paper-Based to Electronic Data Capture and Record Keeping in Clinical Trial Management: Benefits, Challenges and Practical Considerations, Colton Castle

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Trace amine associated receptor 1 (TAAR1), a novel astrocyte receptor for METH-mediated neurotoxicity in HIV-1-associated neurocognitive disorders (HAND), Irma E. Cisneros

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Thymic involution perturbs negative selection and leads to chronic inflammation, Brandon D. Coder B.S.

Intermittent hypoxia induced opioidergic protection of the heart, Juan A. Estrada

Discovery and Characterization of Tetranucleotide Short Tandem Repeats in North American Bears (Ursids), Michelle L. Graham B.S.

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Genetic Diversity of Easter Island (Rapanui) Population from Identifiler® Plus autosomal, Y-filer®, and Y-Plex™ 6 Y-STR Loci, Laura Guadian B.S.

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Advanced Problem Solving in the Biotherapeutics Industry: Parameters influencing the delivery of a novel cell therapy product and exploration of a new method for determining activity of Clostridium histolyticum collagenase, a wound debridement enzyme, Melanie A. Harris B.S.

The Effects of Known PCR Inhibitors on Droplet Digital PCR Performance, William Patrick Kolar

MIEN1 Drives Breast Cancer Invasion by Regulating Cytoskeletal-Focal Adhesions Dynamics, Marilyne F. Kpetemey B.S.

Investigation of Anterior Cruciate Ligament Fibroblast Biomarkers for Cell Characterization by Immunohistochemistry, Tanya Lerma

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Intercellular Nef transfer and HIV-1 infection of astrocytes, Xiaoyu Luo

Evaluating Noise and the Implications of Methodology in the Analytical Threshold Designation for Forensic Genetic Analysis, Ashley N. Malone B.S.

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Analysis of Patient Practices and Attitudes towards Compliance with Contact Lens Storage Cases in Relation to Microbial Contamination Levels, Sarah B. Ndedi

Possible Fluoride Toxicity in North America: a paleopathological assessment and discussion of modern occurrence, Elizabeth A. Nelson

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The Analysis of Current Recruitment Methods: Measuring the Potential of Social Media in Clinical Research Trials, Denise T. Nguyen

Polymorphism of Y-STR haplotypes is governed by patrilineal ancestry combined with effects of male migration, Michael R. Nolan

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Cell line authentication and contamination assessment for human cell cultures, Andrea Ormos B.S.

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The Flip-Flop of AMPA Receptors in Retinal Ganglion Cell Survival, Yong H. Park

Neuroprotective Effects of Brn3b in PC12 Cells and Retinal Ganglion Cells under Glaucomatous Conditions, Nitasha R. Phatak

Dietary Curcumin And Caloric Restriction As Interventions For The Reversal Of Age Associated Functional Decline, Marjana R. Sarker

Antioxidants, Exercise, and Brain Function, Akram Sidhu

Pathological Mechanisms of Retinal Ischemia/Reperfusion Injury and Potential Targets of Neuroprotection, Sean M. Silverman

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Population Variances in the Whole Mitochondrial Genome Impacting Capture for Human Identification, Lisa A. Skandalis B.S.

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Increasing Knowledge of Patients in Clinical Trials Through New Means of Communication, Jordan E. Skrivanek

Next-Generation Sequencing of Culture Negative Bronchoalveolar Lavage Reveals the Presence of Potentially Pathogenic Microorganisms, Ashley D. Smith B.S.

Psalmotoxin-1 and nonproton ligand interactions with acid-sensing ion channels, Rachel N. Smith B.S.

Characterization of the interactions of guanidine compounds with the human GABA-A ρ1 receptor, Heather D. Snell

The Effects of Chronic Intermittent Hypoxia on Oxidative Stress and Inflammation, Brina D. Snyder B.S.

Mitochondrial Genetics and Function among Men Screened for Prostate Cancer, Marc L. Sprouse

Mechanisms by which 17β-Estradiol (E2) suppress neuronal cox-2 expression, Winfred Stacey

Selection of an Ancestry-Informative Marker (AIM) Panel of INDELs, Lindsey M. Thompson B.S.

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Assessment of Health Literacy and Potential Barriers Regarding Acceptance of the Human Papillomavirus (HPV) Vaccine Among Parents/Guardians, Brittany Vo-Le

Study of Kinematics in Individuals with Autism Spectrum Disorder and Developmental Coordination Disorder, Bylinda Vo-Le

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Development of a Comprehensive Massively Parallel Sequencing Panel of Single Nucleotide Polymorphism and Short Tandem Repeat Markers for Human Identification, David H. Warshauer

Role of ΔFosB in nucleus of the solitary tract (NTS) in cardiovascular adaptations to chronic intermittent hypoxia (CIH) in rats, Qiong Wu M.B.B.S.

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Increasing Patient Recruitment Rates for Family Health History Support Tools, Julia Zhang

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Anatomical Variation of the Inferior Mesenteric Vein’s Drainage Pattern, Mina Zilaie B.S.

Theses/Dissertations from 2014

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Effects of Amicon Ultra-4 Centrifugal Devices on DNA Yield From Bone Samples and Effects of Amplicon Rx Post-PCR Treatment onRelative Florescence Units Obtained During Capillary Electrophoresis, Marie B. Amiel

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Role of catecholaminergic A2 neurons of nucleus of the solitary tract(NTS) in cardiovascular and respiratory adaptations to chronic intermittent hypoxia (CIH) in rats, Chandra Sekhar Bathina

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Osteopathic Management of Mild Leg Length Inequality with Heel Lift Therapy: A Pilot Study Analyzing Altered Gait Kinetics and Kinematics, Sebastiaan M. Bens

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The Role of Glycogen Synthase Kinase-3β in the Regulation of Mitochondrial Membrane Permeability, Morgan M. Brooks B.A.

Anti-Tumor Immune Responses Against MTLn3 Mammary Adenocarcinoma, KiahRae J. Carter

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Antioxidants, Exercise, APOE Genotype and Brain Function, Kiran Chaudhari

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Intravenous pyruvate to protect heart and brain during closed-chest resuscitation and recovery from cardiac arrest, Brandon H. Cherry

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Involvement of Caspase-7 in Photoreceptor and Retinal Ganglion Cell Death, Shreyasi Choudhury M.S.

Physical and Biochemical Factors Affecting the Recovery and Analysis of DNA from Human Skeletal Remains, Laura Gaydosh Combs B.A., M.A.

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Factors that Impact Patient Enrollment in Clinical Trials, Phong Duong B.A.

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Maternal Mortality in Sub-Saharan Africa: Steps Towards Millennium Developmental Goals, Inanaboyai U. Eghieye

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Effects of pH on Binding of DNA Using the PrepFiler BTA Forensic DNA Extraction Kit on the AutoMate Express Forensic DNA Extraction System, Erin E. Ferguson

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All-cause and CVD-specific mortality associated with allergic rhinitis and allergic asthma: a retrospective cohort study, Subi Gandhi MPH

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Typing Success of Short Tandem Repeat Loci on Skeletal Remains: Comparison of the AmpFLSTR® Identifiler® Plus and GlobalFiler™ PCR Amplification Kit., Stephanie A. Garcia

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Identifying barriers to enrollment and strategies to increase enrollment at a community-based cancer treatment center, Sheila R. Gokul

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The Three "R"s of Research, Frank P. Goodman

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Intravenous Pyruvate to Prevent Renal Injury Following Cardiac Arrest and Resuscitation, Roger A. Hollrah M.S.

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Extracellular Proliferating Cell Nuclear Antigen as a Marker and Therapeutic Target for Cancer Stem Cells., Nathan C. Horton

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Allele Characterization of Fifteen Short Tandem Repeat Loci of North American Golden (Aquila Chysaetos) and Bald (Haliaeetus leucocephalus) Eagles using Next-Generation Sequencing, Taylor E. Howard

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The Role of IL-23 in Regulating the Recruitment and Function of Phagocytic Cells during Listeria monocytogenes infection, Mohanalaxmi Indramohan M.S.

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Estimating Human DNA Concentration in the Presence of Metal Ion Inhibitors: A Comparison of the Quantifiler® Human DNA Quantification Kit and the Investigator® Quantiplex Kit., Andrea H. Jeffries

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Evaluation of Molecular Techniques Using a Synthetic Mitochondrial Genome, Jessica L. Koenig

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Allele Characterization of Ten Short Tandem Repeat Loci of North American Bears (Ursids) Using Next-Generation Sequencing, Mckensie Kreutzer

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Pharmacological Assessment of Novel Phenylacetamide as a Sigma 1 Receptor Ligand, Maninder Malik

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Shale Gas Production and Surface Water: An Exploratory Case Study On Drinking Water in the Dallas And Fort Worth Metroplex 2001 - 2012, Naomi M. Meier M.S.

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A Comparative Review of Screening, Consent, and Trial Visits and Follow-up Practices in Cardiovascular Dual Antiplatelet Therapy Drug, Device, and Registry Studies at Legacy Heart Center and The Heart Hospital Baylor Plano, Ismail S. Mohiuddin B.S.

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STR Typing of Reference Samples with Rapid DNA technology, Andrea B. Moore

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NEUROPROTECTIVE PROPERTIES OF SIGMA-1 RECEPTOR IN GLAUCOMA, Brett H. Mueller III

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Role of C/EBP Homologous Protein in Photoreceptor and Retinal Ganglion Cell Death, Sonali R. Nashine M.S.

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The Disadvantageous Interrelationship between Lenticular Mitoprotection and Epithelial-Mesenchymal transition via Nuclear Beta catenin, Sudha Neelam M.S.

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Utilization and Access to Healthcare Services Among People Living with Spinal Cord Injuries in the Community, Shayan Noorani B.A.

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Changes in the Microbial Community as a Potential Indicator of Clandestine Drug Operations., Tanisha N. Payne

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Correlation of End-Tidal Carbon Dioxide to Neurological Outcome in Out-of-Hospital Cardiac Arrest, Sabrina D. Phillips B.S.

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Improvement of Data Quality through Source Data Verification in Physical Therapy Research, Kalyssa M. Pollard

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A Pragmatic Work Flow for Manual Medical Chart Review: A Systematic Literature Review, Taoran Qiu B.S.

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Effect of CD44 Expression on T Cell Acute Lymphocytic Leukemia, Ronny R. Racine B.S.

Resilience Over Time in a Longitudinal Study Following Patients with Physical Injury, Evan E. Rainey

Post-transcriptional and Epigenetic Regulation of MIEN1 in Prostate Cancer, Smrithi Rajendiran B.S.

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Changes in Health Knowledge and Lifestyles After Participating in a Research Study, Erica M. Resendes

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Use of Social Media and its Potential for Subject Recruitment in Clinical Trials., Mario C. Reyes

Determination of Genetic Factors Associated with Response to Osteopathic Manipulative Treatment (OMT) in Individuals with Chronic Lower Back Pain (CLBP)., Kayla K. Richardson

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The Role of Estrogen and Estrogen Analogues in Friedreich’s Ataxia Cytoprotection, Timothy E. Richardson

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An Exploratory Investigation of Self-efficacy to Drive While Intoxicated, Matthew E. Rossheim B.A.

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Astrocytes & Ischemic stroke, Gourav Roy Choudhury B.V.Sc & A.H

The role of Angiotensin II in central autonomic and endocrine regulation, Ashwini Saxena M.B.B.S., M.S.

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Lymphatic Pump Treatment Enhances the Lymphatic and Immune System and Ameliorates Disease Severity in a Rat Model of Respiratory Infection, Artur Schander

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Identifying Unique Therapeutic Targets To Rescue Retinal Ganglion Cells From Degeneration After Optic Nerve Crush, Tasneem P. Sharma

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Recruitment Strategies and Fulfilling Enrollment at a Site Management Organization, Mark S. Shell B.S.

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An Overview of Clinical Trials with the Integration and Introduction of an Electronic-Based Records System, Adam T. Stewart B.S.

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Contrasting Force Reduction at the Greater Trochanter Using Different Surgical Procedures for Relief of Greater Trochanteric Pain Syndrome, Victor W. Taylor II

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Authentication of Human Cell Lines and Detection of Human Cell Line Contamination by Cost-Effective Direct Amplification of DNA, Vikram Reddy Vemireddy

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Autonomic nervous control of cardiovascular function during prolonged exercise in humans, Daniel W. White

Theses/Dissertations from 2013

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Evaluation of Health Care Cost and Utilization Project Data (HCUP) in Healthcare Research, Cristianna A. Abilez

Maintaining Balance in Conditions of Sensory Conflict., Lindsay N. Appleby