Date of Award

5-1-2004

Degree Type

Restricted Access Thesis

Degree Name

Master of Science

Department

Graduate School of Biomedical Sciences

First Advisor

John Planz

Second Advisor

Arthur Eisenberg

Third Advisor

Joseph Warren

Abstract

This project had two objectives. The primary one was to establish the haplotype frequency data for the Asian and Southwestern Hispanic populations. This involved developing Y-STR profiles for the entire sample set, establishing haplotype frequencies from the data’s allele frequencies for each of the loci interrogated. This information was then used to calculate the Power of Discrimination for the PowerPlex Y System. The secondary objective was to calculate a mutation rate for this particular Y-STR panel by analyzing established father-son pairs (each pair being one meiosis) and counting the number of differences between the pairs, noting which loci the mutations occurred in.

Comments

W 4.5 S587H 2004

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