Date of Award
Spring 5-2009
Degree Type
Thesis
Degree Name
Master of Public Health
Department
School of Public Health
First Advisor
Dr. Sumihiro Suzuki
Abstract
Treatment outcomes of 28 high risk TKA PJI patients treated with either debridement, six weeks I.V. antimicrobial therapy and prosthesis retention, or same treatment with oral chronic suppressive therapy, to ascertain the effectiveness of oral chronic suppressive therapy were retrospectively reviewed in this study. The 2-year cumulative probability of failure for oral suppressive therapy was 7% (95%CI: 0.04 to 27.5) compared to 42% (95%CI: 17.7 to 66.07) for the control group. Oral suppressive therapy was significantly different than control (P= 0.033). This study underscores the importance of combining oral suppressive therapy in select patients with débridement and six weeks I.V. antimicrobial therapy.
Recommended Citation
McBroom, M. M.
,
"Treatment of Infection in High Risk Patients After Total Knee Arthroplasty by Debridement with Prosthesis Retention: Is Oral Suppressive Therapy the Better Option?" Fort Worth, Tx: University of North Texas Health Science Center;
(2009).
http://digitalcommons.hsc.unt.edu/theses/77