Date of Award

6-1-2008

Degree Type

Restricted Access Professional Report

Degree Name

Master of Science

Field of Study

Cell Biology and Genetics

Department

Graduate School of Biomedical Sciences

First Advisor

Arthur Eisenberg

Second Advisor

John Planz

Third Advisor

Joseph Warren

Abstract

Summary: MICROFIELD COMPANY S.A. is currently developing a non intrusive method of obtaining a reference DNA sample known as Lift & Rub (Figure 1). The Lift & Rub is a self-adhesive security stamp designed to collect a single fingerprint from a known individual that can be used for DNA analyses. Lift & Rub is composed of an adhesive material with a protective film. The Lift & Rub is composed of an adhesive material with a protective film. The Lift & Rub is used in conjunction with an abrasive strip and a product named Dry-Ink, a graphite laminate. Together these items allow for an alternative to the traditional fingerprint collection technique and improve on it by allowing for DNA analysis. The objective of this research is test and maximize the performance of Lift & Rub. Microfield’s Lift & Rub is designed to collect a single fingerprint from a known individual to be used for DNA analyses. The Lift & Rub is intended to provide a full genetic profile of a known individual. This project aims to: 1) establish a standard collection protocol by evaluating empirical data to determine the average DNA yields using various collection techniques; 2) evaluate the reproducibility of DNA profiles obtained; and 3) gauge the overall success rate of obtaining a complete profile.

Comments

W 4.8 M282E 2008

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