Date of Award

8-1-2004

Degree Type

Restricted Access Professional Report

Degree Name

Master of Science

Field of Study

Cell Biology and Genetics

Department

Graduate School of Biomedical Sciences

First Advisor

Joseph Warren

Second Advisor

John Planz

Third Advisor

Arthur Eisenberg

Abstract

This research study was performed at DNAPrint™ in Sarasota. FL. DNAPrint™ is a private laboratory specializing in Single Nucleotide Polymorphism (SNP) technology. Through the use of this technology, they have been able to map SNPs termed Ancestry Informative Markers. This has allowed them to perform additional research with regards to biogeographical ancestry, identification of an individual's physical traits, as well as pharmacogenomics research. In addition, DNAPrint™ also performs paternity and forensic testing using STR markers. This research study was a preliminary investigation of the applicability of Whole genome amplification (WGA) using the GenomiPhi™ DNA Amplification assay in conjunction with available STR kits. The GenomiPhi™ assay was utilized due to its ease and efficiency. Depending upon the outcome of this project, further studies may be conducted to incorporate WGA for use with both their SNP and STR technology.

Comments

W 4.8 L435A 2004

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