Date of Award

5-1-2015

Degree Type

Thesis

Degree Name

Master of Science

Field of Study

Forensic Genetics

Department

Graduate School of Biomedical Sciences

First Advisor

Ranajit Chakraborty

Second Advisor

Bobby L. LaRue

Third Advisor

Robert C. Barber

Abstract

Determination of ancestry using DNA markers is an important issue in DNA forensics. The ability to identify an individual’s ancestry could narrow down the pool of possible individuals involved in a crime. Several types of ancestry informative markers (AIMs) have been suggested in the literature. For this study, Alu markers were used for investigating their utility for Caucasian versus African and Caucasian versus Asian ancestry determinations. Three measures of AIMs were calculated for 42 Alu markers. Rank correlations of these three measures were used for investigating if a smaller number of top-ranked loci can improve ancestry determination. The Alu markers chosen for this study were less informative than anticipated but did show potential for ancestry estimation when all 42 markers were used together.

Comments

D’Auben, Aislinn. Ancestry Informativeness of Alu Markers in Four Populations Relevant for the United States. Master of Science (Biomedical Sciences, Forensic Genetics). April 2015. 36 Pages, 8 tables, 2 figures, 17 references.

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