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Theses/Dissertations from 2018

Detecting and Quantifying Oxidative DNA Damage using MinION Nanopore Sequencing, Alexandra Blessing

Bioengineered Nanoparticles for Targeted Cancer Therapy, Andrew S. Gdowski

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The Phenotype of Cells Expressing Estrogen Receptor Alpha in the Nucleus of the Solitary Tract, Christopher L. Horn

The Effect of Hearing Loss on Balance Control, Victoria Kowalewski

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The Effect of Diet on Craniofacial Growth in Osteogenesis Imperfecta Mouse Model, Summer H. Ladd

SNP Genotyping of Native DNA using Oxford Nanopore MinION Sequencing, Whitney N. Ludwick

Oxazolone as a model to induce edema in the lower limb of rats, Christopher Pastrana

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Spectral Properties of Doxorubicin Doped rHDL Nanoparticles, Sunil Shah

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Analysis of Patient Recruitment Methods for Clinical Trials of Different Heart and Lung Diseases, Oghenevovwero Vovwe Sido

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The Interaction of Type 2 Diabetes and Cognitive Impairment in Mexican Americans: Insights from the Mitochondria, Talisa Silzer

Androgen modulation of CNS during chronic intermittent hypoxia, Brina D. Snyder

Potential Therapeutic Benefits of Cyclical Blood Flow Restriction Exercise: A Novel Adaptation of Remote Ischemic Preconditioning, Justin Daniel Sprick

Relationship Between Clinical Rounding Practices and Patient Perception of Communication in the Intensive Care Unit (ICU), Vanetria D. Stokes

Influence of Environmental Temperature on The Bacterial Microbiomes of Ixodes scapularis Ticks, Santosh Thapa

Autism Spectrum Disorder with and Without Co-Occurring Attention Deficit Hyperactivity Disorder: An Analysis of Pathways to Diagnosis and Intervention in a National Sample, Morgan Thomi

Theses/Dissertations from 2017

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Adaptation of the Genetic Risk Prediction Model BRCAPRO for Primary Care Settings, Philamer M. Atienza

TAARgeting Astrogliosis and Mitochondrial Dysfunction during METH Exposure and HIV-relevant Neuroinflammation, Kathleen Borgmann

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Novel androgen receptor splice variant in the substantia nigra, Jo Garza Contreras

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“Ecstasy” to Addiction: Mechanistic and Reinforcing Effects of Synthetic Cathinone Analogs of MDMA, Sean B. Dolan

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A Survey of Anticoagulation Non-Adherence in Emergency Department Patients Presenting with Atrial Fibrillation, Sean Harla

Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork, Humberto Hernandez

Analysis of patient compliance and progression of diabetic foot ulcer healing, Waasae M. Hussain

Mechanisms of Sympathoexcitation via Hyper-Acute Intermittent Hypoxia in Humans: Implications for Obstructive Sleep Apnea, Noah P. Jouett

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Factors Affecting Study Subject Recruitment and Retention in a Major Depressive Disorder Study, Barbara Karnkowska

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The Association of Health Literacy with the Management of Type 2 Diabetes, Samita Kumar

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Creating novel purification and biochemical characterization protocols for C. collagenase from Clostridium histolyticum, developing a new emergency medicine product, and formulating several novel therapies for chronic and acute wound treatment, Jason P. Mars

The vascular aging of the cerebellum, Christopher L. McElroy

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Endothelin receptor-mediated neurodegeneration in glaucoma, Nolan McGrady

Pain Management After Appendectomy and Cholecystectomy: An Innovative Protocol Using Exparel, Pete Newman

Role of Scavenger Receptor Class B Type 1 in High-Risk Neuroblastoma, Marlyn Panchoo

Tolfenamic acid enhances the anti-proliferative activity of Vincristine in medulloblastoma cell Lines, Shruti Vikas Patil

A Pilot Study into the Impact of Remote Monitoring on the Trial Site, Brendan Paulman

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Measurement of Traumatic Brain Injury (TBI) Inpatient Activity Levels Through Accelerometry, Jeffrey T. Ramsey

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Assisting the Implementation of a Centralized IRB in Multiple Categories of Research at Medical City of Fort Worth, Pawanpreet Randhawa

Genetic profiling of skin microbiomes for forensic human identification, Sarah E. Schmedes

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Approaches to mitochondrial genome sequencing using the oxford nanopore minion device, Kelcie C. Thorson

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Obstacles Associated with Physician Referral of Patients into Clinical Trials, Nick Torrez

Divergent Behavioral Phenotypes in Conditioned Place Preference, Alison N. Wagner

Theses/Dissertations from 2016

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Comparative assessment of IV acetaminophen and conscious sedation for pain relief during invasive cardiac procedures, Zainab I. Alam

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Sponsor Accrual of Investigative Add-On Sites, Eli Arbov

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A Retrospective Analysis and Curricular Mapping Assessment of Student Engagement in Research Design in Classes Offered by the College of Pharmacy at University of North Texas Health Science Center at Fort Worth, Karthikeyan Baskaran

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Benefits, Challenges, and Future Directions: Making the Case for eTMF in Clinical Research, Amber C. Beckham

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Barriers to Completion of a Family Health History Tool and Increasing Subject Retention, Margarett A. Bennett

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Exploring Trabecular Meshwork Molecular Pathogenic Mechanisms In Primary Open Angle Glaucoma And Glucocorticoid Induced Glaucoma, Jaclyn Y. Bermudez

Development and Characterization of Methylene Blue Oleate Salt-Loaded Polymeric Nanoparticles as a Treatment for Glioblastoma, Jessica M. Castañeda-Gill

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Variation in the Branching Pattern of the Internal Iliac Artery, Jeff Chase

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Store operated calcium entry in glomerular mesangial cells and diabetic nephropathy, Sarika Chaudhari

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Sensing and imaging of hyaluronidase activity using a long-lived fluorophore, Rahul Chib

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Submission to the IRB: Will Modified Training Improve the Probability of Successful Submission of IRB Protocols?, Yuhung H. Chou

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Prevention and treatment of diseases: a small molecule discovery and development approach, Dhwanil A. Dalwani

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Implementation of an Updated Standard Operating Procedure For Investigational Product Management, Johnny V. Dang

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Study of Kinematics and Gait in Dynamic Response Feet across Functional K-Level Categories., Russell J. Donevant

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Effect of Phosphorylation on Muscle Physiology and Biophysical Characterization of Mutations Responsible for Familial Hypertrophic Cardiomyopathy, Divya Duggal

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Statins and PCSK9 Inhibitors: How They Have Shaped Medicine, A Comparative Review, Phillip R. Escarsega

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Astrocyte-mediated HIV-1 Tat neurotoxicity and its molecular mechanisms: astrocyte activation and impaired neurogenesis, Yan Fan

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Multiple primary cancers in survivors of adolescent and young adult cancers in the United States, SEER 1973-2012, Lauren R. Hall

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Impact of age on technical and in-hospital outcomes of percutaneous coronary intervention for chronic total occlusions, Rahel Iwnetu

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SR-B1 directed nanoparticles as a drug delivery system for the treatment of triple negative breast cancer, Rebecca A. Johnson

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The Role of Cerebral Oxygenation and Perfusion on Tolerance to Central Hypovolemia, Victoria L. Kay

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Inorganic nanoparticles for applications in biomedical sciences, Bhuvaneswari Koneru

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Comparison of Deparaffinization Methods with DNA Quantification, Raechal P. Leonard

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MaCHTools: Additional functionality for the imputation software MaCH, Jeffrey S. Mitchel Jr.

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The Role of Free Radicals in the Exercise Induced Resetting of the Arterial Baroreflex, Gilbert Moralez

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Human Blood versus Two Commercially Available Blood Substitutes: A Comparative Analysis, Katharine M. Murphy

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Study of Spatiotemporal Orientation and Cross Bridge Kinetics in Ventricular and Skeletal Muscles, Janhavi Nagwekar

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A Cadaveric Investigation of the Dorsal Scapular Nerve, Vuvi H. Nguyen

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The role of exosomes and microRNA in Astrocyte-mediated HIV-1 Tat neurotoxicity, Pejman Rahimian

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Quantitative Proteomic Investigation of Estrogenic Endocrine-Disrupting Effects in the Rat Uterus, Fatima R. Rahlouni

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Multiplex of INDELs for Human Identification Markers, Kelly A. Sage

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The Role of Angiotensin II in Central Control of Blood Pressure and Body Fluid Homeostasis, Brent Shell

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Epigenetic Regulation of Gene Expression in Alzheimer’s disease, Shantanu J. Shewale

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A Novel Multiplex Assay for an Ancestry-Informative Marker (AIM) Panel of INDELs, Sarah A. Sturm

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Identifying Risk Factors for 30-Day Readmissions in Patients with Cirrhosis, Stephen L. Tan

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Views on Clinical Trials, Bryan Q. Tran

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Tip110 is required for embryonic stem cell survival and embryonic development, Amanda J. Whitmill

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The effects of temperature on the microbiome of the ectoparasite Amblyomma americanum, Kelsi R. Willis

Extracellular Superoxide Dismutase Indirectly Enhances the Release of Immature Neutrophils from the Murine Bone Marrow, Alexandra R. Witter

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Admixture Effects on Coevolved Metabolic Systems, Roxanne R. Zascavage

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Selection of Highly Informative Markers for Apportionment of Ancestry and Population Affiliation, Xiangpei Zeng

Theses/Dissertations from 2015

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A guanidine dietary supplement influences pH sensitivity and NSAID activity in acid-sensing ion channels, Amruta S. Agharkar

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Developmental and Internal Validation of a Mitochondrial DNA Direct Amplification Kit for Forensic Reference Samples, Alessandra Alicea-Centeno B.S.

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Analysis of Efficiency and User Satisfaction Following the Introduction of Digital Source Documents and Resources in a Clinical Research Setting, Marlena C. Alosi

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Comparison of Next Generation Sequencing Methodology on the Ion PGM™ System Performance versus that on the Sanger Sequencing Method for HV1 and HV2 Regions of mtDNA, Wendy C. Argueta B.S.

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Risk of Hematopoietic Cancer Associated Mortality among Workers in the Poultry Slaughtering and Processing Industries, Saritha Bangara M.P.H

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Healthcare Provider Barriers to Family Health History Clinical Decision Support Tools, Victoria R. Baria

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Effect of Collagenase Type 2 and Proteinase K Digestion on DNA Yield from Bone Samples Purified on the EZ1 Advanced XL, Lisa C. Barrett

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Comparative study of the physical symptoms following bilateral mastectomy with immediate breast reconstruction and delayed breast reconstruction, Ritika U. Bhat M.B.B.S.

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Glucocorticoid Receptor Mediated CRH Gene Repression, Shreyas Bhave

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Evaluation of NK Cell – Astrocyte Interactions: Potential Role in HIV-Associated Neurocognitive Disorders and HIV- Associated Dementia, Kelly E. Bowen B.A.

Aging of the Thymic Epithelial Progenitor Pool is Determined by the p63-FoxN1 Regulatory Axis, Preston I. Burnley

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Converting from Paper-Based to Electronic Data Capture and Record Keeping in Clinical Trial Management: Benefits, Challenges and Practical Considerations, Colton Castle

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Trace amine associated receptor 1 (TAAR1), a novel astrocyte receptor for METH-mediated neurotoxicity in HIV-1-associated neurocognitive disorders (HAND), Irma E. Cisneros

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Thymic involution perturbs negative selection and leads to chronic inflammation, Brandon D. Coder B.S.

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Characterization and Optimization of Nanoparticles for Polynucleotide delivery, Bhavani Saranya Conjeevaram Nagarajan

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Ancestry Informativeness of Alu Markers in Four Populations Relevant for the United States, Aislinn G. D'Auben

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Intermittent hypoxia induced opioidergic protection of the heart, Juan A. Estrada

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Observations of impaired autonomic regulation of arterial pressure in obese Zucker rats: focus on changes in the nucleus of the solitary tract., Guangchao Fu

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Discovery and Characterization of Tetranucleotide Short Tandem Repeats in North American Bears (Ursids), Michelle L. Graham B.S.

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Genetic Diversity in Sioux Indians of South Dakota with 21 Autosomal STR Loci and Their Forensic Utility, Nicole C. Grubb

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Genetic Diversity of Easter Island (Rapanui) Population from Identifiler® Plus autosomal, Y-filer®, and Y-Plex™ 6 Y-STR Loci, Laura Guadian B.S.