Date of Award
Restricted Access Thesis
Master of Science
Graduate School of Biomedical Sciences
This project had two objectives. The primary one was to establish the haplotype frequency data for the Asian and Southwestern Hispanic populations. This involved developing Y-STR profiles for the entire sample set, establishing haplotype frequencies from the data’s allele frequencies for each of the loci interrogated. This information was then used to calculate the Power of Discrimination for the PowerPlex Y System. The secondary objective was to calculate a mutation rate for this particular Y-STR panel by analyzing established father-son pairs (each pair being one meiosis) and counting the number of differences between the pairs, noting which loci the mutations occurred in.
"Haplotype for Promega's Powerplex®Y System for Southwestern Hispanic and Asian Populations" Fort Worth, Tx: University of North Texas Health Science Center;