Date of Award


Degree Type


Degree Name

Master of Science

Field of Study

Clinical Research Management


Graduate School of Biomedical Sciences

First Advisor

Robert T. Mallet

Second Advisor

Peter B. Raven


Newborn screening (NBS) results in a surplus of blood samples in the form of dried bloodspots (DBS). Texas’s “opt-in” policy requires mothers’ permission for the state to store DBS samples for research. A cross-sectional study was performed on post-partum mothers in North Texas to determine the effect of the mothers’ demographics, knowledge, attitudes, and decisions about NBS and DBS storage on trust in Texas’ ability to make good decisions regarding bloodspot research. The aforementioned trust in the Texas government was strongly associated with trust in Texas to keep the babies’ information private, belief that using DBS for public health was beneficial, and trust in Texas to de-identify their babies’ DBS. Medicaid coverage also showed a slight association with this trust. Overall, mothers who are supportive of public health research using de-identified specimens such as DBS are more confident in the Texas’s ability to make the right choices regarding DBS storage.


Nguyen, Huy David D., A Cross-Sectional Study on Factors Affecting Maternal Trust in Texas Government to Make Good Decisions About Newborn Screening and Dried Bloodspot Storage. Master of Science (Clinical Research Management), December, 2015, 54 pp., 4 tables, 1 figure, bibliography, 10 titles.